This is the most central province of Cuba and its northern and southern coastlines are washed by the waters of the Atlantic and the Caribbean respectively.
It has a fuller history, being another of Velazquez's original townships. From the town's pleasant main square wander two blocks south to the Parroquial Mayor, a venerable yellow towered church whose early 16th-century origins make it the country's oldest, and across to the nearby Museo de Arte Colonial.
Boutique Hotel next to Sancti Spiritus' Iglesia Mayor. The house used to be the residence of the renowned doctor Don Rudesindo García Rijo, after whom the hotel is named.